B2128 - The impact of iodine perchlorate and thiocyanate status on childhood cognitive and thyroid function - 01/05/2014
Aims
We therefore propose to i) study the impact of iodine, perchlorate and thiocyanate (another iodine-thyroid disruptor) levels on adolescent thyroid function and IQ using the 882 ALSPAC children who have urine samples available from age 15 who also have had thyroid function measured and their IQ assessed. ii) We also propose to measure perchlorate and thiocyanate in the ALSPAC mums from urine taken during the first trimester, to see if they impact on offspring neuro-cognitive development at age 8 and childhood thyroid function age 7. We are proposing to measure these in the 2,300 women who have iodine measured already (or imminently) by the Rayman group. This has already been discussed with Margaret Rayman and Sarah Bath and we will proceed with a formal collaboration if this study is approved.