B2128 - The impact of iodine perchlorate and thiocyanate status on childhood cognitive and thyroid function - 01/05/2014

B number: 
B2128
Principal applicant name: 
Prof Peter Taylor (University of Cardiff, UK)
Co-applicants: 
Dr Colin Dayan (University of Cardiff, UK), Prof John Lazarus (University of Cardiff, UK), Dr Onyebuchi Okosieome (University of Cardiff, UK), Dr Lewis Braverman (Boston University, USA), Ass. Prof Elizabeth Pearce (Boston University, USA)
Title of project: 
The impact of iodine, perchlorate and thiocyanate status on childhood cognitive and thyroid function.
Proposal summary: 

Aims

We therefore propose to i) study the impact of iodine, perchlorate and thiocyanate (another iodine-thyroid disruptor) levels on adolescent thyroid function and IQ using the 882 ALSPAC children who have urine samples available from age 15 who also have had thyroid function measured and their IQ assessed. ii) We also propose to measure perchlorate and thiocyanate in the ALSPAC mums from urine taken during the first trimester, to see if they impact on offspring neuro-cognitive development at age 8 and childhood thyroid function age 7. We are proposing to measure these in the 2,300 women who have iodine measured already (or imminently) by the Rayman group. This has already been discussed with Margaret Rayman and Sarah Bath and we will proceed with a formal collaboration if this study is approved.

Date proposal received: 
Monday, 16 December, 2013
Date proposal approved: 
Thursday, 1 May, 2014
Keywords: 
Cognitive Function, Thyroid, Iodine
Primary keyword: 
Iodine