B2144 - Studying the Population Prevalence of Large Mosaic Chromosomal Rearrangements in Children - 23/01/2014

B number: 
B2144
Principal applicant name: 
dR Matthew Hurles (Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK)
Co-applicants: 
Dr Daniel A King (Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK), Dr Nic Timpson (University of Bristol, UK), Dr Tom Gaunt (University of Bristol, UK)
Title of project: 
Studying the Population Prevalence of Large Mosaic Chromosomal Rearrangements in Children.
Proposal summary: 

Aims:

We propose to collaborate with ALSPAC to compare the prevalence of large (1 Mb or larger) mosaic deletions, duplications and loss of heterozygosity events between the ALSPAC population sample and children in our congenital disease project, The Deciphering Developmental Disorders (DDD) Study.

Date proposal received: 
Monday, 13 January, 2014
Date proposal approved: 
Thursday, 23 January, 2014
Keywords: 
Cognitive Function
Primary keyword: 
Genetics