B2164 - ALSPAC Epigenomics Strategic Award 2014 - 13/02/2014
B number:
B2164
Principal applicant name:
Dr Caroline Relton (University of Bristol, UK)
Co-applicants:
Prof George Davey Smith (University of Bristol, UK), Dr Tom Gaunt (University of Bristol, UK), Dr Susan Ring (University of Bristol, UK), Prof Kate Tilling (University of Bristol, UK)
Title of project:
ALSPAC Epigenomics Strategic Award 2014.
Proposal summary:
Aims
* To enhance ALSPAC to incorporate detailed annotation of epigenomic features and additional epigenomic profiling to provide an internationally leading, widely accessible, population-based reference resource.
To exploit the unique scientific opportunities afforded by ALSPAC to identify epigenetic signatures of exposure, track their persistence over time, across generations and evaluate their relationship with development and disease.
To assess the genetic contribution to DNA methylation variation through leadership of a Genome-Wide Association Study Consortium
To develop a "statistical tool-kit" to facilitate the analysis of population-based epigenetic data
Date proposal received:
Saturday, 8 February, 2014
Date proposal approved:
Thursday, 13 February, 2014
Keywords:
Primary keyword:
Epigenetics