Our proposed study of pursuit and saccade eye movemets in the ALSPAC cohort will allow many hypotheses to be tested but initially we will concentrate on:

Variation in anti-saccade task accuracy with IQ (as per Evdokimifdis et al)

Variation in smooth pursuit and saccade function with PLIKS score (as part of Zammit et al's programme)

Variation in sacccade fuction as a measure of executive control, according to previous exposure to potential neurotoxins such as tobacco, alocohol, cannabis, other drugs

Variation in oculomotor parameters according to previous stressful experiences - this is relevant to the current popularity of eye-movemet based thereapy for post-traumatic stress disorder.

Variations in oculomotor control according to genotype for specific candidate genes and as the phenotype for GWAS studies of genetic predictors of oculomotor control

Further researc questions will be developed in line with current literature and withstrategic funding calls.