Research Question:

Are infants born to the ALSPAC cohort who received one or more courses of antibiotics during the fetal and early life more likely to develop psychological problems during their preschool years when compared to children who were not exposed to antibiotics?

Hypothesis:

It is hypothesized that antibiotic exposure during fatal and early life will disrupt the natural development of the human microbiome during a critical window of vulnerability. This will result in behavioural changes which will be observed as a higher prevalence of psychological problems in preschool years.