B2385 - Genome wide association study for physical activity and sedentary behaviour - 05/02/2015

B number: 
B2385
Principal applicant name: 
Dr Rebecca Richmond (University of Bristol, UK)
Co-applicants: 
Dr Nic Timpson (University of Bristol, UK), Miss Mary Ward (University of Bristol, UK)
Title of project: 
Genome wide association study for physical activity and sedentary behaviour
Proposal summary: 

This analysis will form part of an expanded meta-analysis for self-reported moderate and vigorous leisure time activity and sedentary behaviour. Our first goal is to capture a dichotomous trait corresponding to moderate and vigorous leisure activity. Such activity would not include occupation-related activity (i.e. shoveling, heavy-lifting) and/or light leisure activity (i.e. walking, gardening). The second goal is to capture all aspects of sedentary behaviour for which we defined four traits; three dichotomous traits, reflecting sedentary behaviour at work, home and during commuting, and one continuous trait: TV viewing.Separate GWAS analyses will be run for male and female offspring and the mothers. Covariates included in the models are age and body mass index.

Date proposal received: 
Friday, 30 January, 2015
Date proposal approved: 
Thursday, 5 February, 2015
Keywords: 
Physical Activity
Primary keyword: 
GWAS