B2398 - Genomics of Neuropsychiatric Traits in Children and Adolescents MRC IEU project - 05/03/2015

B number: 
B2398
Principal applicant name: 
Christie Burton (University of Toronto, Canada)
Co-applicants: 
Prof Paul Arnold (University of Toronto, Canada), Jennifer Crosbie (University of Toronto, Canada), Russell Schachar (University of Toronto, Canada), Dr Evie Stergiakouli (University of Bristol, UK), Prof George Davey Smith (University of Bristol, UK)
Title of project: 
Genomics of Neuropsychiatric Traits in Children and Adolescents: MRC IEU project
Proposal summary: 

Aims & Hypotheses

The overall aim of our research is to identify genetic variants associated with a neuropsychiatric traits in children using community-based samples. We are interested in three specific traits: obsessive-compulsive traits, ADHD traits and response inhibition as measured by the Stop-Signal Task. Given that response inhibition is an endophenotype for ADHD, we expect that identifying genetic variants associated with response inhibition will also help us identify genetic variants associated with ADHD.

Date proposal received: 
Friday, 20 February, 2015
Date proposal approved: 
Thursday, 5 March, 2015
Keywords: 
GWAS, Mental Health
Primary keyword: 
ADHD