B4758 - The impact of intergenerational transmission of mental health problems on childrens development in early life - 02/12/2024

B number: 
B4758
Principal applicant name: 
Isabel Morales-Munoz | University of Birmingham (United Kingdom)
Co-applicants: 
Prof Steven Marwaha, Prof Joht Singh Chandan, Prof Georgios Gkoutos, Dr Nicola Adderley
Title of project: 
The impact of intergenerational transmission of mental health problems on children’s development in early life
Proposal summary: 

Mental health problems can run in families, and children with parents or grandparents who struggle with mental health are at a higher risk of facing challenges in their development. For example, when parents or grandparents have mental health problems, it can sometimes lead to poorer outcomes for children. However, it’s not yet clear whether this is due to a general pattern of mental health issues or due to specific mental health conditions only. We also don’t fully understand whether some aspects of a child’s development, like their behaviour, health, or learning, are more affected than others. Importantly, not all children with a family history of mental health problems will have developmental issues. Therefore, it’s crucial to figure out what helps protect children and build resilience against these risks. To explore this, we are using data from the ALSPAC, which includes information on three generations: grandparents (G0), parents (G1), and children (G2). We aim to find out if children with a family history of mental health problems are more likely to face challenges in early childhood, such as having a difficult temperament, poor health, behavioural issues (like trouble sleeping), or delays in language development.

Impact of research: 
Our research can lead to improvements in understanding, prevention, and intervention for developmental challenges linked to the intergenerational transmission of mental health problems. For example, our research can help identify vulnerable children early, enabling timely support and monitoring. Further, understanding protective factors can empower families and communities to build resilience in children, offering practical tools and strategies to buffer against the negative effects of mental health problems in the family. Finally, this research could inform healthcare and education policies, ensuring resources are directed to programs that support children and families affected by mental health challenges across generations.
Date proposal received: 
Friday, 29 November, 2024
Date proposal approved: 
Monday, 2 December, 2024
Keywords: 
Mental health - Psychology, Psychiatry, Cognition, Mental health, Statistical methods, Development, Offspring, Psychology - personality, Sleep