B4730 - Mapping the Spatiotemporal Trajectories of Pain Across the Lifespan - 04/11/2024

B number: 
B4730
Principal applicant name: 
Matt Fillingim | McGill University (Canada)
Co-applicants: 
Etienne Vachon-Presseau
Title of project: 
Mapping the Spatiotemporal Trajectories of Pain Across the Lifespan
Proposal summary: 

Our project aims to understand how pain develops and changes throughout a person's life, from adolescence to older age. We use a modeling approach to map when and where pain is likely to occur at different ages, integrating data from major global pain studies.

Most pain studies currently focus on specific areas like the head, abdomen, or back, often treating each area separately. In contrast, our research will create a comprehensive model to track how pain spreads across the body over time. This model will identify key ages when pain patterns change and help establish "normal" pain levels for different age groups. These benchmarks will be valuable for doctors, as they will make it easier to spot unusual pain patterns and critical life stages when pain transitions, such as moving from internal to musculoskeletal pain, are most likely to occur.

Impact of research: 
The likely impact of this research will be a deeper, more comprehensive understanding of how pain develops and evolves across the lifespan. By establishing normative pain trajectories, our work can offer critical benchmarks for identifying atypical pain patterns early, facilitating timely interventions and personalized treatment approaches. Additionally, by integrating psychosocial factors into our models, we aim to uncover key determinants of pain variability, which could inform targeted public health strategies and clinical practices. Ultimately, this research has the potential to improve pain management, reduce chronic pain burden, and enhance quality of life across diverse populations.
Date proposal received: 
Wednesday, 30 October, 2024
Date proposal approved: 
Thursday, 31 October, 2024
Keywords: 
Epidemiology, Behaviour - e.g. antisocial behaviour, risk behaviour, etc., Bone disorders - arthritis, osteoporosis, Chronic fatigue, Diabetes, Gastrointestinal, Mental health, Obesity, Pain, Respiratory - asthma, Statistical methods, Ageing, BMI, Bones (and joints), Sex differences, Sleep, Statistical methods