Religiosity and spirituality are an important factor in the lives of many people. Previous research, using relatively small sample sizes in cross-sectional studies, has found that a high degree of belief in the importance of religion/spirituality was associated with both a thicker cortex and a larger pial surface area in persons at high risk for familial depression. We plan to see if these specific findings replicate in a much larger cohort. We also plan to do an exploratory analysis, where we will look at all of the brain MRI variables measured in ALSPAC to see if any are associated with the religion/spirituality variables measured in ALSPAC.