B4604 - Genetic determinants of perinatal depression and its long-term impact on the family unit - 14/05/2024

B number: 
B4604
Principal applicant name: 
Nic Timpson | ALSPAC
Co-applicants: 
Dr Alex Kwong, Dr Chia-Yen Chen, Dr Sharon Chen, Dr Catherine Mak
Title of project: 
Genetic determinants of perinatal depression and its long-term impact on the family unit
Proposal summary: 

Depression is one of the most common medical complications in the perinatal period. Previous studies have suggested long-term consequences on infant, child and future offspring development. However, few studies have investigated the relationship between perinatal depression, offspring and partner outcomes in a multi-generational large scale longitudinal study. Furthermore, in order to fully understand the impact of perinatal depression, more research is needed to understand the genetics of perinatal depression.

Impact of research: 
This research will give insight to the associations between perinatal depression exposure, on offspring development and family unit and provide a foundation for human genetic research on depression around pregnancy and childbirth
Date proposal received: 
Tuesday, 30 April, 2024
Date proposal approved: 
Wednesday, 8 May, 2024
Keywords: 
Mental health - Psychology, Psychiatry, Cognition, Pregnancy - e.g. reproductive health, postnatal depression, birth outcomes, etc., Statistical methods, Mothers - maternal age, menopause, obstetrics