B4328 - Depression and hypertension comorbidity sleep as a potential mediator - 24/05/2023
Depression and hypertension commonly co-occur. This comorbidity may be explained by HPA axis dysregulation which has associations with both hypertension and depression. Additionally, sleep problems are a known cause of HPA axis dysregulation, therefore, sleep may serve as a transdiagnositic marker, and potentailly intervention point, for both disorders. This research will focus on childhood and adolescence as previous research has only examined this relationships in adults, despite these conditions being prevalent in younger groups. Additionally, adulthood is a time when these conditions are already well-established. Through examining a younger sample, we can study the directionality and mediation of this relationship at a time when both conditions start to emerge.