B4089 - Genome-wide association study of suicidal thoughts and attempts - 08/06/2022
Genome-wide association studies (GWAS) have been instrumental in highlighting associations between genetic variants and 1000s of traits. A recent GWAS of suicide attempts by the psychiatric genetics consortium (PGC) Suicide Working Group identified 2 genome-wide significant loci (Mullins et al., 2021). The PGC are expanding their work to separate GWAS of suicidal ideation and attempts and are seeking additional cohorts. We plan to include ALSPAC data from the mothers and the children in the next round of analysis for suicide attempts and suicidal ideation PGC GWAS. We will prepare summary statistics from the GWAS to be shared with the PGC and perform subsequent in cohort analysis. This will be a big step towards incorporating ALSPAC data into psychiatric genetics. The summary statistics will contain no identifiable information.