B3937 - Scrambling ALSPAC genotype data for use in genetic course practicals - 29/11/2021

B number: 
B3937
Principal applicant name: 
Gibran Hemani | MRC Integrative Epidemiology Unit
Co-applicants: 
Josine Min, Lavinia Paternoster
Title of project: 
Scrambling ALSPAC genotype data for use in genetic course practicals
Proposal summary: 

We teach on many genetic epidemiology courses, and we need realistic genetic data that is relatively large and also non-sensitive for many of these projects. We have used a modified version of ALSPAC G1 individuals in the past in which genomes have been scrambled. In doing so, a representative set of samples with realistic correlation patterns is developed but contains no individuals that correspond to any real participants

Impact of research: 
Imparts useful practical skills to course participants
Date proposal received: 
Friday, 26 November, 2021
Date proposal approved: 
Monday, 29 November, 2021
Keywords: 
Genetic epidemiology (including association studies and mendelian randomisation), None apply, Gene mapping, GWAS, Statistical methods, Genetic epidemiology, Genome wide association study