B3845 - Early-life factors for elevated blood pressure later in life - 26/08/2021

B number: 
B3845
Principal applicant name: 
Peige Song | Zhejiang University (China)
Co-applicants: 
Miss Leying Hou, Miss Qian Yi
Title of project: 
Early-life factors for elevated blood pressure later in life
Proposal summary: 

Elevated blood pressure, or hypertension, has become a major public health concern globally. Evidence shows that blood pressure tracks into adulthood. However, most epidemiology research to date on hypertension has focused on risk factors from single aspects, but it is becoming increasingly evident that early-life factors may come from multiple sources, such as society, community, family and individual. For example, a positive association between rapid weight gain and elevated blood pressure in both children and adults has been widely observed. Other community-based evidence shows that lower early-life environment exposure to residential greenness has been found to be independently associated with elevated blood pressure. Until recently, the combined effects and interplay of individual and community-level factors on the developmental programming of blood pressure are still limited, and further research is needed.

Impact of research: 
This research will expand its impact in the research field of public health, paediatric hypertension, environmental health.
Date proposal received: 
Monday, 16 August, 2021
Date proposal approved: 
Thursday, 26 August, 2021
Keywords: 
Epidemiology, Behaviour - e.g. antisocial behaviour, risk behaviour, etc., Developmental disorders - autism, Diabetes, Eating disorders - anorexia, bulimia, Eczema, Hypertension, Mental health, Obesity, Pregnancy - e.g. reproductive health, postnatal depression, birth outcomes, etc., Respiratory - asthma, Metabolomics, Statistical methods, Ageing, Biological samples -e.g. blood, cell lines, saliva, etc., Childhood - childcare, childhood adversity, Development, Endocrine - endocrine disrupters, Environment - enviromental exposure, pollution, Epigenetics, Fathers, Genetic epidemiology, Growth, Hormones - cortisol, IGF, thyroid, Injury (including accidents), Biomarkers - e.g. cotinine, fatty acids, haemoglobin, etc., Intelligence - memory, Mothers - maternal age, menopause, obstetrics, Metabolic - metabolism, Nutrition - breast feeding, diet, Offspring, Psychology - personality, Physical - activity, fitness, function, Puberty, Sex differences, Siblings, Birth outcomes, Sleep, Social science, Statistical methods, Telomere, Vision, Blood pressure, BMI, Bones (and joints), Breast feeding, Cardiovascular, Cohort studies - attrition, bias, participant engagement, ethics