B3824 - Multivariate Genetic Study of Impulsivity and Binge Drinking through Late adolescence and Early Adulthood - 05/07/2021
Binge drinking behaviors in late adolescence and early adulthood have been shown to be important indicators of risk for developing problems with alcohol use and related consequences which may extend beyond early adulthood. Binge drinking behaviors are also thought to be influenced, in part, by impulsive personality traits such that more impulsive adolescents and emerging adults tend to binge drink more heavily, more frequently, and beyond early adulthood. However, the connection between impulsive personality and binge drinking has been clouded to some extent in past research because there is generally not a widely agreed upon “best” way to measure impulsive personality. Additionally, this measurement issue may obscure our ability to detect genetic influences on impulsive personality and binge drinking and their connection across the lifespan. The proposed study seeks to clarify the role that genetic factors might play in this relationship by using results from pre-existing genetic studies of impulsive personality and alcohol use to define genetic risk factors that reflect more succinct traits (e.g., the drive to behave impulsively in response to emotions and rewards, and the inability to stop or control these drives). These re-defined genetic risk factors will then be used to determine the extent to which genetic influences for impulsive personality predict changes in binge drinking across late adolescence and early adulthood in the ALSPAC sample.