B3403 - Validation of alcohol score as a negative control - 07/11/2019
B number:
B3403
Principal applicant name:
Tom Richardson | MRC Integrative Epidemiology Unit (United Kingdom)
Co-applicants:
Ms Si Fang, Prof George Davey Smith
Title of project:
Validation of alcohol score as a negative control
Proposal summary:
We are interested in understanding the effects of alcohol consumption on cardiovascular disease risk. To do this we have been constructing a genetic risk score in the UK Biobank study, which we wish to validate in ALSPAC as a negative control.
Impact of research:
A better understanding of how alcohol influences cardiovascular disease risk.
Date proposal received:
Wednesday, 6 November, 2019
Date proposal approved:
Thursday, 7 November, 2019
Keywords:
Epidemiology, Hypertension, GWAS, Methods - e.g. cross cohort analysis, data mining, mendelian randomisation, etc.