B3351 - Broad Antisocial Behavior Consortium BroadABC - meta-analysis of antisocial phenotypes - 05/08/2019
B number:
B3351
Principal applicant name:
Hannah Sallis | MRC IEU
Co-applicants:
Prof Marcus Munafo
Title of project:
Broad Antisocial Behavior Consortium (BroadABC) - meta-analysis of antisocial phenotypes
Proposal summary:
The BroadABC has been created to combine the results of multiple genome-wide association studies of broad antisocial behavior (measured by symptom counts of antisocial personality disorder, ratings of aggression, conduct problems, delinquency, psychopathic personality etc) in meta-analyses in order to increase the probability of detection of genetic variants associated with individual differences in liability to antisocial behaviors. For phase 2 our aim is to include at least ~150,000 individuals.
Impact of research:
Date proposal received:
Friday, 2 August, 2019
Date proposal approved:
Monday, 5 August, 2019
Keywords:
Genetic epidemiology (including association studies and mendelian randomisation), Behaviour - e.g. antisocial behaviour, risk behaviour, etc., GWAS, Genome wide association study