B3221 - Lung function curve over the life-course using longitudinal data from multiple cohorts - 20/12/2018

B number: 
B3221
Principal applicant name: 
Anne-Elie CARSIN | ISGlobal, Barcelona (EspaƱa)
Co-applicants: 
Title of project: 
Lung function curve over the life-course using longitudinal data from multiple cohorts
Proposal summary: 

Lung function curves have been explored mainly using cross-sectional data and for selected age ranges. There is no cohort that covers the full life-course for lung function yet, this is challenged by the time and effort needed to follow individuals from birth to death. The ALEC project gives us a unique opportunity to fit lung function curves longitudinally gathering all the lung function data available among all the cohorts which participated to the ALEC project, in a real world setting.

Impact of research: 
The results of the present project will contribute to the development of lung function curves in the general population. This is a highly relevant issue given no longitidunal study of the lung function growth and decline over a life time has yet been described, and the fact that lung function is associated with numerous health problems throughout life, including morbidity and mortality. Furthermore, we expect that our results will be published in a high impact scientific journal.
Date proposal received: 
Friday, 30 November, 2018
Date proposal approved: 
Thursday, 6 December, 2018
Keywords: 
Epidemiology, Addiction - e.g. alcohol, illicit drugs, smoking, gambling, etc., Obesity, Respiratory - asthma, Statistical methods, Ageing, Cohort studies - attrition, bias, participant engagement, ethics, Growth