B3209 - Effects of metabolome on puberty timing - 20/11/2018
B number:
B3209
Principal applicant name:
Juliana dos Santos Vaz | IEU, University of Bristol for the duration of fellowship (to 28/02/19); permanent affiliation Federal University of Pelotas, Pe (Brazil)
Co-applicants:
Prof Debbie Lawlor, Dr Maria Carolina Borges, Dr Ahmed Elhakeem, Dr Kate Tilling, Dr Joshua Bell, Dr Diana Santos Ferreira, Dr Amy Taylor, Dr Laura Howe
Title of project:
Effects of metabolome on puberty timing
Proposal summary:
Impact of research:
Substantial evidence, including from Mendelian Randomization, shows greater BMI causes earlier age at puberty. This research will help us to understand whether that is due to greater BMI altering metabolic profiles which in turn affect age at puberty. We will publish findings in peer reviewed journals and present at conferences. Clinical or public health impact will depend on our specific findings and these in relation to other research.
Date proposal received:
Friday, 16 November, 2018
Date proposal approved:
Tuesday, 20 November, 2018
Keywords:
Epidemiology, Puberty; Cardiovascular disease, Metabolomics, NMR, Statistical methods