B3195 - GWA META-ANALYSIS ON ASTHMA PLUS ECZEMA PHENOTYPES - INTERACTION WITH EARLY TOBACCO SMOKING EXPOSURE - 18/10/2018
B number:
B3195
Principal applicant name:
Ashley Budu-Aggrey | MRC Integrative Epidemiology Unit (IEU)
Co-applicants:
Dr Raquel Granell, Dr Lavinia Paternoster, Dr Marie-Hélène Dizier , Emmanuelle Bouzigon, Florence Demenais
Title of project:
GWA META-ANALYSIS ON ASTHMA PLUS ECZEMA PHENOTYPES - INTERACTION WITH EARLY TOBACCO SMOKING EXPOSURE
Proposal summary:
There are an increasing number of studies on the broad phenotype of allergic disease where individuals suffer from asthma, eczema or hay fever, presenting with at least one of these diseases. This study aims to identify genetic markers for individuals with both asthma and eczema and investigate how early exposure to tobacco smoke affects this phenotype.
Impact of research:
Date proposal received:
Wednesday, 17 October, 2018
Date proposal approved:
Thursday, 18 October, 2018
Keywords:
Genetic epidemiology (including association studies and mendelian randomisation), Eczema, Pregnancy - e.g. reproductive health, postnatal depression, birth outcomes, etc., Respiratory - asthma, GWAS, Dermatology, Environment - enviromental exposure, pollution, Genetic epidemiology, Genetics, Genome wide association study