B3174 - Transmission of health within families via the gut microbiome - 06/09/2018
B number:
B3174
Principal applicant name:
Kaitlin Wade | MRC Integrative Epidemiology Unit (United Kingdom)
Co-applicants:
Ana Zhu
Title of project:
Transmission of health within families via the gut microbiome
Proposal summary:
Obesity, happiness and smoking patterns are among some of the phenomenon that seem to be influenced by an individualâs social network, exhibiting a âthree degrees of influenceâ property. Transmission of gut bacteria could be a potential mechanism for transmission of genetic traits from one individual to another. Hence, it could potentially provide a plausible mechanistic explanation for some of the social patterns transmitted within social networks. Understanding the extent of gut microbiome transmission can help us elucidate some of social patterns that we observe in the human population.
Impact of research:
The gut microbiome is a novel and modifiable risk factor for health and disease that may have clinical importance and potentially facilitate therapeutic development to improve health and reduce the burden of disease.
Date proposal received:
Friday, 31 August, 2018
Date proposal approved:
Tuesday, 4 September, 2018
Keywords:
Epidemiology, microbiology and bioinformatics, Behaviour - e.g. antisocial behaviour, risk behaviour, etc., Gut microbiome, health indicators, GWAS, Statistical methods, Metagenomics, Biological samples -e.g. blood, cell lines, saliva, etc., BMI, Microbiome