B3136 - Impulsivity as a Risk Mechanism in the ALSPAC Cohort Longitudinal Augmentation - 27/06/2018
B number:
B3136
Principal applicant name:
James MacKillop | McMaster University (Canada)
Co-applicants:
Dr. Marcus Munafo
Title of project:
Impulsivity as a Risk Mechanism in the ALSPAC Cohort: Longitudinal Augmentation
Proposal summary:
Impulsivity is a multidimensional psychological trait that has been linked to addictive disorders and other mental
health conditions. However, most of the studies to date have used cross-sectional designs. Our current ALSPAC project added impulsivity phenotypes to the cohort at one time point and this proposal is to add the same measures to a second time point. This will allow us to examine impulsivity's causal/consequential role as a risk mechanism.
Impact of research:
If successful,the proposed study has the potential to further implicate the role of specific forms
of impulsivity in the development of several highly prevalent psychiatric conditions and to illuminate these processes as mechanisms by which genetic variation and environmental experiences confer risk and protection. Given the quality of the ALSPAC cohort and anticipated dataset, the findings,positive or negative, will have a major impact on this line of scientific inquiry.
Date proposal received:
Saturday, 16 June, 2018
Date proposal approved:
Tuesday, 19 June, 2018
Keywords:
Mental health - Psychology, Psychiatry, Cognition, Addiction - e.g. alcohol, illicit drugs, smoking, gambling, etc., Behaviour - e.g. antisocial behaviour, risk behaviour, etc., Mental health, Obesity, Sexually transmitted diseases, chlamydia, gonorrhoea, DNA sequencing, GWAS, Biological samples -e.g. blood, cell lines, saliva, etc., Biomarkers - e.g. cotinine, fatty acids, haemoglobin, etc., Psychology - personality, Blood pressure, BMI, Cardiovascular, Childhood - childcare, childhood adversity, Cognition - cognitive function, Genetics, Genomics, Genome wide association study