2504 - Methylomics of adolecent anorexia nervosa
B number:
2504
Principal applicant name:
Helge Frieling | Hannover Medical School - Department of Psychiatry (Germany)
Co-applicants:
Vaness Buchholz, Prof. Nadia Micali, Rory Wilson
Title of project:
Methylomics of adolecent anorexia nervosa
Proposal summary:
Anorexia nerovsa is a severe mental illness most often affecting adolescent girls. The etiology of the disorder is complex and involves genetics as well as environmental aspects. We have shown that epigenetic factors can contribute to the disorder. In the current Project, we have already measured epigenetic marks (i.e. DNA methylation) on a genome-wide level in girls participating in a psychotherapy-trial for anorexia nervosa. We want to compare our findings to the data from girls participating in the ALSPAC study that show no signs of an eating disorder.
Date proposal received:
Monday, 3 August, 2015
Date proposal approved:
Friday, 14 August, 2015
Keywords:
Genetics, Eating disorders - anorexia, bulimia, Epigenetics, Genetics - e.g. epigenetics, mendelian randomisation, UK10K, sequencing, etc.