Nearly one in ten school-age children struggles with learning to read and spell. Reading disorders can run in families and there may be a genetic cause for some children. Children with reading disorders are at risk for anxiety and depression, as well as lower job obtainment in adult years. Despite affecting millions of children much is still unknown, including exactly which genes cause reading disorders. We think that different behavioral profiles of reading disorders result from different gene variations. Furthermore, there is evidence reading disorders are resulting from a number of genes acting together. We will explore how different behavioral profiles relate to gene variants, as well as how genes interact with each other in children with reading disorders.