B2679 - DNA methylation profile in children with varying degrees of sun exposure - 03/05/2017
B number:
B2679
Principal applicant name:
Carolina Bonilla | IEU (United Kingdom)
Co-applicants:
Dr. Hannah Elliott
Title of project:
DNA methylation profile in children with varying degrees of sun exposure
Proposal summary:
This project will investigate whether exposure to sunlight affects DNA methylation in peripheral blood samples of children of European descent living in Southwest England, searching for differential epigenetic signals between sun exposed and sun protected individuals. We will additionally examine how DNA methylation relates to pigmentary traits (some of them risk factors for skin cancer) and vitamin D levels.
Date proposal received:
Wednesday, 20 April, 2016
Date proposal approved:
Tuesday, 26 April, 2016
Keywords:
Epidemiology, Epigenetics, Dermatology, Environment - enviromental exposure, pollution, Genetics - e.g. epigenetics, mendelian randomisation, UK10K, sequencing, etc., Sex differences, pigmentation, vitamin D, ultraviolet radiation, sun exposure