B2716 - Impact of dietary xanthine consumption on myopia in mothers and children from the ALSPAC Cohort - 14/07/2016

B number: 
B2716
Principal applicant name: 
Cathy Williams | School of Social and Community Medicine
Co-applicants: 
Dr Ian Flitcroft, Christine Wildsoet, Prof Jeremy Guggenheim, Kate Northstone
Title of project: 
Impact of dietary xanthine consumption on myopia in mothers and children from the ALSPAC Cohort
Proposal summary: 

The current generation of school students and young adults are destined to be significantly more short-sighted (myopic) than their parents. Several possible treatments to slow down the development of short-sightedness (myopia) have been identified by scientists. One of these (7-methylxanthine), taken as a tablet, is closely related to both caffeine, which is found in many drinks, e.g., Coca-Cola, as well as in tea and coffee, and another chemical that is found in chocolate. We have little information about how effective these other chemicals might be in treating myopia, but most of us eat or drink something containing these chemicals everyday. This project is designed to see if caffeinated drinks and/or chocolate might protect us to some degree from developing myopia. If we find this effect, this result may help us develop new ways of treating myopia.

Date proposal received: 
Friday, 8 July, 2016
Date proposal approved: 
Wednesday, 13 July, 2016
Keywords: 
Ophthalmology, Myopia, Statistical methods, Vision, Myopia, diet