B2749 - ADHD and DNA methylation a repeated measures EWAS - 28/09/2016
B number:
B2749
Principal applicant name:
Esther Walton | University of Bristol - IEU
Co-applicants:
Title of project:
ADHD and DNA methylation: a repeated measures EWAS
Proposal summary:
Attention-deficit/hyperactivity disorder (ADHD) is a prevalent developmental disorder, associated with a range of long-term impairments. However, the potential role of DNA methylation, an epigenetic mechanism, in ADHD symptoms is currently unclear. We plan to examine peripheral measures of DNA methylation at birth and ADHD symptoms (4–18 years) in different cohorts (GenerationR, ALSPAC, other PACE cohorts). Findings could lend novel insights into the epigenetic landscape of ADHD symptoms.
Date proposal received:
Tuesday, 20 September, 2016
Date proposal approved:
Wednesday, 28 September, 2016
Keywords:
Mental health - Psychology, Psychiatry, Cognition, Behaviour - e.g. antisocial behaviour, risk behaviour, etc., Developmental disorders - autism, Mental health, ADHD, Epigenetics, Development, Genetics - e.g. epigenetics, mendelian randomisation, UK10K, sequencing, etc., ADHD