B2782 - How the early environment interacts with prenatal adversity and genetic susceptibility to moderate the risk for anxious and depr - 10/11/2016

B number: 
B2782
Principal applicant name: 
Hannah Sallis | MRC IEU, University of Bristol (UK)
Co-applicants: 
Dr Ashley Wazana, Dr Rebecca Pearson, Dr Jonathan Evans, Dr Michael Meaney, Prof Marinus van IJzendoorn, Dr Eszter Szekely, Dr Henning Tiemeier
Title of project: 
How the early environment interacts with prenatal adversity and genetic susceptibility to moderate the risk for anxious and depr
Proposal summary: 

The project aims to investigate how early life stressors influence later childhood psychopathologies, in particular symptoms of anxiety and depression. The interaction between genotype and prenatal adversity will also be investigated.

Date proposal received: 
Tuesday, 1 November, 2016
Date proposal approved: 
Wednesday, 9 November, 2016
Keywords: 
Mental health - Psychology, Psychiatry, Cognition, Mental health, Genomics - structural variants, Statistical methods, Childhood - childcare, childhood adversity, Development, Environment - enviromental exposure, pollution, Genetics - e.g. epigenetics, mendelian randomisation, UK10K, sequencing, etc., Methods - e.g. cross cohort analysis, data mining, mendelian randomisation, etc., Sex differences, Statistical methods