B2837 - Predicting Risk Resilience for Social and Visceral Health in Response to Childhood Abuse - 27/04/2017

B number: 
B2837
Principal applicant name: 
Stephen Porges | The Kinsey Institute at Indiana University Bloomington (United States)
Co-applicants: 
Jacek Kolacz, PhD, Jerry Jesseph, MD, Sue Carter, PhD
Title of project: 
Predicting Risk & Resilience for Social and Visceral Health in Response to Childhood Abuse
Proposal summary: 

The link between childhood abuse and development of social problems and gastrointestinal disorders is well documented. However, some children exposed to abuse go on to lead relatively undisturbed lives, while others are totally devastated. This analysis will seek to understand whether risk and resilience to traumatic experiences may have an evolutionary foundation by using a framework provided by Polyvagal Theory, which outlines the biological link between neural circuits that regulate body states including gastrointestinal functions (and disorders of other subdiaphragmatic organs) and the regulation of social engagement behaviors (Porges, 2001; 2007; 2011). Within this framework, the function of neural systems that regulate body state during the perinatal period may determine individual differences in the long term consequences of severe childhood stressors and traumatic experiences. Thus, the goal of the proposed analyses is to examine whether perinatal variables, related to visceral regulation, will contribute to the risk for gastrointestinal disorders and social problems following childhood abuse.

Date proposal received: 
Tuesday, 7 February, 2017
Date proposal approved: 
Monday, 20 February, 2017
Keywords: 
Pathology, Behaviour - e.g. antisocial behaviour, risk behaviour, etc., Gastrointestinal, Pain, Statistical methods, Biomarkers - e.g. cotinine, fatty acids, haemoglobin, etc., Childhood - childcare, childhood adversity, Statistical methods