Macroeconomic conditions or business cycle status during year of birth have been found to have diverse impacts on later life health (e.g. cognitive function in later life, Doblhammer & van den Berg 2013). Epigenetic modifications are important biological regulatory mechanisms that undergo widespread remodeling during development, are susceptible to modification, and may mediate the impact of early-life environmental factors on later life health. We aim to examine to examine whether macroeconomic status at birth is associated with altered DNA methylation, particularly epigenetic age acceleration, in adults.