B2893 - Is BP variability related to pregnancy outcome - 01/06/2017

B number: 
B2893
Principal applicant name: 
Laura A Magee | St. George's, University of London (UK)
Co-applicants: 
Richard McManus
Title of project: 
Is BP variability related to pregnancy outcome?
Proposal summary: 

Outside pregnancy, how much blood pressure varies is associated with the risk of heart attack, stroke and similar health problems.
In the CHIPS Trial (Control of Hypertension In Pregnancy Study) of 987 women with high blood pressure that was there before pregnancy or that developed in pregnancy, we found that the more blood pressure varied, the greater the risks for the mother, with possibly reduced risks for the baby. We are seeking to confirm whether these findings can be replicated in another dataset.

Date proposal received: 
Monday, 29 May, 2017
Date proposal approved: 
Wednesday, 31 May, 2017
Keywords: 
Clinical research/clinical practice, Hypertension, Pregnancy - e.g. reproductive health, postnatal depression, birth outcomes, etc., Statistical methods, Birth outcomes, Blood pressure, Cardiovascular