B2909 - Ageing Lungs in European Cohorts Project- EWAS on Lung Function - 12/07/2017

B number: 
B2909
Principal applicant name: 
Nicole Probst-Hensch | Swiss Tropical and Public Health Institute, University of Basel (Switzerland)
Co-applicants: 
Dr. Anna Beckmeyer-Borowko
Title of project: 
Ageing Lungs in European Cohorts Project- EWAS on Lung Function
Proposal summary: 

The Ageing Lung in European Cohorts project (ALEC) uses longitudinal DNA methylation data obtained from population-based cohorts (SAPALDIA, ECRHS, NFBC) of various adult age groups. The search for relevant methylation signals is being conducted in the context of agnostic as well as candidate-gene based approaches.

Date proposal received: 
Wednesday, 5 July, 2017
Date proposal approved: 
Sunday, 9 July, 2017
Keywords: 
Genetics, Addiction - e.g. alcohol, illicit drugs, smoking, gambling, etc., Allergy, Behaviour - e.g. antisocial behaviour, risk behaviour, etc., Respiratory - asthma, Epigenetics, Statistical methods, Ageing, Biological samples -e.g. blood, cell lines, saliva, etc., Cohort studies - attrition, bias, participant engagement, ethics, Genetics - e.g. epigenetics, mendelian randomisation, UK10K, sequencing, etc.