Prenatal maternal stressors can affect a child’s later life health (Van den Bergh et al., 2017). Candidate gene studies indicate DNA methylation is a potential underlying mechanism (Nagarajan et al., 2016), but to date no individual locus survived multiple testing correction in epigenome-wide studies (Rijlaarsdam et al., 2016). Thus, we aim to examine the association between prenatal maternal stress (depression, anxiety, and stressful life events) and offspring DNA methylation in a meta-analytical setting (the Pregnancy and Childhood Epigenetics, PACE, Consortium).