B3018 - Examination of the relationship between atopic latent profiles and asthma-eczema-hay-fever broad phenotype - 30/01/2018
B number:
B3018
Principal applicant name:
Raquel Granell | University of Bristol
Co-applicants:
Lavinia Paternoster, Hannah Clark
Title of project:
Examination of the relationship between atopic latent profiles and asthma-eczema-hay-fever broad phenotype
Proposal summary:
A recent study has identified 136 genetic markers associated with all three allergic diseases (asthma, hay-fever, eczema). Another study has shown that patients fall into different groups of allergic disease, for example some may have only asthma and eczema, and others may have only eczema and hay-fever etc. This project is aiming to find out if any of these genetic markers are associated with any particular groups of disease.
Date proposal received:
Monday, 11 December, 2017
Date proposal approved:
Tuesday, 12 December, 2017
Keywords:
Genetics, Allergy, Eczema, Respiratory - asthma, Statistical methods, Childhood - childcare, childhood adversity, Genetics - e.g. epigenetics, mendelian randomisation, UK10K, sequencing, etc., wheezing, asthma, eczema, atopy, rhinitis, hay-fever