B857 - Replication of SNPs identified in recent GWAS for intelligence - 10/07/2009
B number:
B857
Principal applicant name:
Dr Danielle Posthuma (VU University Medical Centre of Amsterdam, Europe)
Co-applicants:
Dr Barbara Franke (VU University Medical Centre of Amsterdam, Europe), Dr Alejandro Arias Vasquez (VU University Medical Centre of Amsterdam, Europe)
Title of project:
Replication of SNPs identified in recent GWAS for intelligence.
Proposal summary:
Using an existing IQ GWAS dataset, we have conducted a targeted candidate gene and candidate region analysis for intelligence. We identified several new genes in previously identified candidate regions. We currently have three other replication samples, and would also like to add the ALSPAC study as an independent relication.
We will need to have access (through an ALSPAC collaborator) to the (results of association analysis of) IQ scores of all individuals and to the genotypes of SNPs in three genes that were obtained using the Illumina 317k platform.
Date proposal received:
Friday, 10 July, 2009
Date proposal approved:
Friday, 10 July, 2009
Keywords:
GWAS
Primary keyword: