Sarah Medland, a collaborator from the Queensland Institute of Medical Research, has found some interesting associations between genetic variants and peg board times in her sample of Australian twins. ALSPAC is one of the few cohorts in the world with this measure and genome-wide association data, and we would like to perform a joint GWAS meta-analysis of peg-board times in both our samples, followed by replication in the remainder of the ALSPAC cohort if necessary. We already have previous ALSPAC exec approval to conduct a GWAS of handedness, and have done so, however the results of this scan have been disappointing to date- possibly due to the crude nature of this phenotype (i.e. "What hand do you hold a pencil in?"). It is possible that a more fine scale quantitative measure like peg board times, might be a cleaner phenotype in which to work with and produce better evidence of association with genetic variants. As an addendum, I am particularly keen to foster these smaller collaborations as it means that ALSPAC features prominently on any high profile publications relating to this work (c.f. our recent 2D4D paper in American Journal of Human Genetics, Medland et al. 2010) whereas this is not always the case when part of larger consortia