B1120 - Prenatal and perinatal factors and hyperactivity outcomes in children in the ALSPAC cohort - 09/02/2011

B number: 
B1120
Principal applicant name: 
Dr Blanca Bolea (University of Bristol, UK)
Co-applicants: 
Prof Alan Emond (University of Bristol, UK), Prof Glyn Lewis (University of Bristol, UK)
Title of project: 
Prenatal and perinatal factors and hyperactivity outcomes in children in the ALSPAC cohort.
Proposal summary: 

Three CCEI subscales, free-floating anxiety, depression and somaticism, were administered to the study mothers as part of a larger questionnaire at 18 and 32 weeks gestation and then when their study child was age 8 weeks, followed by 8, 21 and 33 months. In a recently submitted paper (under review at Psychological Medicine), Davies, Evans, Heron and Lewis undertook factor analysis of the 23 CCEI symptoms at all six time points in the same dataset. They reported a three factor solution with remarkably robust factor structure across the six time points, especially for the two dominant factors which at every time point comprised symptoms typical of depression/generalised anxiety (factor 1) and of panic (factor 2). We aim to analize the association of these factors in the mothers with the "ADHD" trajectories in their children.

Date proposal received: 
Wednesday, 9 February, 2011
Date proposal approved: 
Wednesday, 9 February, 2011
Keywords: 
ADHD, Mental Health
Primary keyword: