The STELAR collaboration was established by Asthma UK to harmonize data collection on asthma and related allergic outcomes in five UK birth cohorts (ALSPAC, Manchester Asthma and Allergy Study, Isle of Wight Study, Ashford Study, Aberdeen SEATON study). A previous MRC grant funded data collection sweeps in three of these studies (IoW, MAAS and SEATON). This proposal is primarily to use machine learning tools (in collaboration with Microsoft, Cambridge) to develop novel phenotyping methods to better understand the endophenotypes of asthma.