B1310 - Relationships between childhood social environment and sexual maturation and the role therein of the IGF axis - 02/02/2012

B number: 
B1310
Principal applicant name: 
Dr Daniel Nettle (University of Newcastle, ROW)
Co-applicants: 
Dr Ian Rickard (Not used 0, Not used 0)
Title of project: 
Relationships between childhood social environment and sexual maturation, and the role therein of the IGF axis
Proposal summary: 

Objectives

  1. Derive a measure of social adversity prior to five years of age (see Nettle et al. 2011)
  2. Determine whether social adversity predicts age at sexual maturity/peak height velocity
  3. Determine whether social adversity predicts attitude to sexual relationships in adolescence and risk-taking behaviour
  4. Determine whether social adversity predict the age at/probability of the cohort member first having sexual relationships
  5. Determine whether social adversity predicts IGF-I and IGFBP-3 measured at age 5/8
  6. Determine whether IGF-I and IGFBP-3 measured at age 5/8 mediate or moderate the relationships described in 2-4 above
Date proposal received: 
Thursday, 2 February, 2012
Date proposal approved: 
Thursday, 2 February, 2012
Keywords: 
IGF, Sexual Health
Primary keyword: