B1362 - Reciprocal genome-wide Mendelian Randomization of smoking Body Mass Index and educational attainment - 10/05/2012
B number:
B1362
Principal applicant name:
Dr Dave Evans (University of Bristol, UK)
Co-applicants:
Prof Debbie A Lawlor (University of Bristol, UK), Prof Marcus Munafo (University of Bristol, UK), George Davey-Smith (University of Bristol, UK), Prof Peter Visscher (University of Queensland, Australia, ROW), Prof Joel Hirschhorn (Harvard School of Public Health, USA), Ms Rachel A Clark (Harvard School of Public Health, USA)
Title of project:
Reciprocal genome-wide Mendelian Randomization of smoking, Body Mass Index and educational attainment
Proposal summary:
The aim of the project is to inform the relationship between smoking, BMI and educational attainment using bidirectional genome-wide Mendelian Randomization.
Required ALSPAC data: All available smoking and BMI data on the mothers and the children as well as educational attainment level of mother. Genome-wide SNP data will be required to calculate genome-wide allelic scores in the mothers and offspring.
Date proposal received:
Thursday, 10 May, 2012
Date proposal approved:
Thursday, 10 May, 2012
Keywords:
Mendelian Randomisation, Smoking Obeisty, Education, GWAS, Obesity, Smoking
Primary keyword: