B1512 - Is the effect of maternal smoking on childhood lung function mediated by nicotine A Mendelian Randomisation approach - 14/02/2013

B number: 
B1512
Principal applicant name: 
Prof Seif Shaheen (Barts and London School of Medicine, UK)
Co-applicants: 
Dr Robert Walton (Queen Mary, University of London, UK), Prof John Henderson (University of Bristol, UK), Prof George Davey Smith (University of Bristol, UK), Prof John Holloway (University of Southampton, UK), Dr Susan Ring (University of Bristol, UK)
Title of project: 
Is the effect of maternal smoking on childhood lung function mediated by nicotine? A Mendelian Randomisation approach.
Proposal summary: 

Aims:

To investigate the association between child (fetal) CYP2A6 genotype and lung function and interactions with reported maternal smoking.

Date proposal received: 
Thursday, 14 February, 2013
Date proposal approved: 
Thursday, 14 February, 2013
Keywords: 
Genes, Asthma
Primary keyword: