B1540 - GWAS meta-analysis on childrens sleep problems - 28/03/2013
B number:
B1540
Principal applicant name:
Dr Henning Tiemeier (Erasmus University Medical Center, Rottterdam, the Netherlands, Europe)
Co-applicants:
Dr Irene Pappa (Erasmus University Medical Center, Rottterdam, the Netherlands, Europe)
Title of project:
GWAS meta-analysis on children's sleep problems.
Proposal summary:
AIM:
To study the genetic basis of sleep problems in children (Caucasian ancestry only).
HYPOTHESES:
A GWAS meta-analysis on children's sleep problems will provide a powerful tool to reveal novel pathways and enhance our understanding on the architecture of these problems.
Family based and twin studies reveal high genetic heritability of sleep problems but so far, little evidence exists on particular genes and related pathways.
EXPOSURE VARIABLES:
No.
OUTCOME VARIABLES:
-Child Behavior Checklist (CBCL) : Scale Sleep Problems.
-Any other instrument with 3 or more comparable items to the above scale.
CONFOUNDING VARIABLES
- age, gender
Date proposal received:
Thursday, 28 March, 2013
Date proposal approved:
Thursday, 28 March, 2013
Keywords:
GWAS, Sleep
Primary keyword: