B2120 - Investigation of parent of origin effects in relation to DNA methylation - 05/12/2013
B number:
B2120
Principal applicant name:
Mr Hashem Shibab (University of Bristol, UK)
Co-applicants:
Dr Tom Gaunt (University of Bristol, UK), Dr Caroline Relton (University of Bristol, UK), Prof George Davey Smith (University of Bristol, UK)
Title of project:
Investigation of parent of origin effects in relation to DNA methylation.
Proposal summary:
Aim:
1) identify novel parent of origin variants in relation to DNA methylation in ALSPAC;
2) investigate the effects of known/established parent of origin variants (related to common disease) in relation to DNA methylation in ALSPAC;
3) Investigate the relationship between genotype, methylation and phenotype to better understand parent-of-origin effects on phenotype.
Date proposal received:
Thursday, 28 November, 2013
Date proposal approved:
Thursday, 5 December, 2013
Keywords:
Primary keyword:
Epigenetics