B2151 - Epigenome wide association study of BMI - replication of 278 identified markers using methylation data from ARIES - 30/01/2014

B number: 
B2151
Principal applicant name: 
Dr Rebecca Richmond (University of Bristol, UK)
Co-applicants: 
Dr Caroline Relton (University of Bristol, UK), Dr John C Chambers (Imperial College London, UK), Dr Alexander Drong (University of Bristol, UK)
Title of project: 
Epigenome wide association study of BMI - replication of 278 identified markers using methylation data from ARIES.
Proposal summary: 

Proposal for Replication:

The 278 CpG markers associated with BMI at p[GCout]less than 10-7 in the primary analysis will be taken forward to the replication stage to be analysed or looked up in a set of independent replication cohorts. We propose undertaking this replication using methylation data on the ALSPAC mothers involved in the ARIES project.

Date proposal received: 
Sunday, 26 January, 2014
Date proposal approved: 
Thursday, 30 January, 2014
Keywords: 
BMI
Primary keyword: 
Epigenetics