B2182 - Detecting serum metabolite-associated gene sets within ALSPAC - 27/02/2014
B number:
B2182
Principal applicant name:
Dr Edward Mountjoy (University of Bristol, UK)
Co-applicants:
Dr Tom Gaunt (University of Bristol, UK), Dr Jose A Seoane (University of Bristol, UK)
Title of project:
Detecting serum metabolite-associated gene sets within ALSPAC.
Proposal summary:
1. Assess elastic nets, random forests and support vector machine regression models for their applicability to the outlined problem.
2. Identify sets of genes that contribute to each metabolic phenotype.
3. Carry out functional analyses on identified gene sets.
4. Compare gene sets between time points and between similar metabolite measures.
Date proposal received:
Friday, 21 February, 2014
Date proposal approved:
Thursday, 27 February, 2014
Keywords:
Methods
Primary keyword:
Metabolomics