The purpose of using the ALSPAC data is to demonstrate the new methods on real Mendelian randomization studies done using ALSPAC. ALSPAC is one of the largest repositories of data used for Mendelian randomization. More importantly, ALSPAC contains individual-level values, a necessity for Kang et al.'s methods. Utilizing ALSPAC data would allow us to validate some of the causal conclusions already made with ALSPAC using the new robust methods as well as allow opportunities for novel causal effects that were previously not possible due to the presence of invalid instruments.