B4317 - Air pollution and inflammation in childhood adolescence and early adulthood - 24/04/2023

B number: 
B4317
Principal applicant name: 
Ana Goncalves Soares | MRC IEU, University of Bristol (United Kingdom)
Co-applicants: 
Anna Goulding, Dr Ruby Tsang
Title of project: 
Air pollution and inflammation in childhood, adolescence, and early adulthood
Proposal summary: 

Exposure to air pollution has been associated with poorer cardiovascular health and cardiovascular disease, and inflammation is one of the postulated mechanisms of this relationship. Most studies have investigated the association between air pollution and inflammation using C-reactive protein (CRP), particularly in adulthood. Evidence in younger ages and using other inflammatory markers is limited. This study will explore the association between air pollution and inflammation from childhood to early adulthood using different inflammatory markers.

Impact of research: 
Date proposal received: 
Monday, 24 April, 2023
Date proposal approved: 
Monday, 24 April, 2023
Keywords: 
Epidemiology, Air pollution, Statistical methods, Biomarkers - e.g. cotinine, fatty acids, haemoglobin, etc.