The prevalence of multimorbidity increases with age. Therefore, to prevent it and mitigate its impacts, we need to understand how multiple factors at different stages of the life course affect an individual’s health trajectory with ageing.

Currently, an important knowledge gap exists in this area as most research has focused on single life stages and/or single diseases, and often only at adult ages when multimorbidity appears. This overlooks the sequence and dynamic development of comorbidities in the life course.

We will address this gap by creating trajectories of multimorbidity by disease, physiological function and medication usage across all life stages.