B4261 - Genomics metabolomics and inflammatory markers and Eating Disorders and related behaviours across the life span and generations - 27/03/2023

B number: 
B4261
Principal applicant name: 
nadia micali | Mental health Services, Capital Region of Denmark ( Denmark )
Co-applicants: 
Majken Jensen Prof, Cynthia Bulik, Prof, Moritz Herle, Mohammed Abdulkadir, Alfonso Buil, Dorte Helenius Mikkelsen, Stefana Aicoboaie
Title of project: 
Genomics, metabolomics and inflammatory markers and Eating Disorders and related behaviours across the life span and generations
Proposal summary: 

Eating Disorders (ED) (full and partial syndrome anorexia nervosa and bulimia nervosa and binge eating disorder) are life- threatening illnesses that start in adolescence and affect between one and two in ten adolescents and young adults. There is a lack in our understanding of why eating disorders develop, which affects our ability to develop treatment and adequately prevent eating disorders. This project builds on our previous studies in ALSPAC, showing that metabolism and growth might play a role in the development of eating disorders. We aim to combine metabolic function, body composition, blood and inflammatory markers, as well as genetic information to understand progression and development of eating disorders and related symptoms in the 3 generations of ALSPAC participants. This study will be fundamental in understanding how eating disorders develop and progress across the life span.

Impact of research: 
Date proposal received: 
Monday, 6 March, 2023
Date proposal approved: 
Monday, 27 March, 2023
Keywords: 
Epidemiology, Eating disorders - anorexia, bulimia, Statistical methods, Genetic epidemiology